| 1541 | De Soto crosses the Mississippi at or near the Fourth Chickasaw Bluff, where Memphis now stands.
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| 1673 | Needham and Arthur enter East Tennessee. Joliet and Marquette descend the Mississippi from Wisconsin River to 34° N. latitude and stop at Chickasaw Bluffs.
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| 1682 | La Salle builds Fort Prud'homme on First Chickasaw Bluff near mouth of Hatchie River.
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| 1692 | Martin Chartier, one of La Salle's men, after some years' stay with Shawnee of Cumberland Valley, travels from French Lick up Cumberland River and overland to Virginia.
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| 1711 | Eleazer Wiggan, English trader, establishes trade with Overhill Cherokee.
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| 1714 | Charleville, French trader, operates a trading post at Great French Lick where Nashville now stands.
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| 1730 | Sir Alexander Cuming negotiates first treaty between English and Cherokee. Group of chiefs go with him to England.
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| 1736 |
Christian Priber reaches Cherokee town of Great Tellico, plans to establish his "Kingdom of Paradise."
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| 1748 | Dr. Thomas Walker of Virginia explores vicinity of present Kingsport.
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| 1750 | Dr. Thomas Walker and party explore upper East Tennessee and pass through Cumberland Gap into Kentucky. Walker was the first explorer to record discovery of what he later named Cumberland Gap.
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| 1756 | Major Andrew Lewis builds Virginia fort near Chota, Cherokee capital.
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| 1757 | Fort Loudoun, near Virginia fort, completed; first Anglo-American fort in Tennessee to be garrisoned.
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| 1758 | Presbyterian Mission established at Fort Loudoun by Rev. John Martin.
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| 1760 | War between English and Cherokee. Indians take Fort Loudoun. Daniel Boone commissioned by Henderson and Co. to scout East Tennessee.
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| 1761 |
Peace is made between English and Cherokee.
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| 1763 | Ensign Timberlake, Sergeant Sumter, Ostenaco, and two of his warriors visit England.
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| 1764 | Henry Scaggs (Scoggins) explores Tennessee region as representative of Henderson & Co.
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| 1766 | Col. James Smith leads exploring party which discovers Stone's River, named for Uriah Stone, one of the party.
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| 1768 | Treaty of Hard Labour between English and Cherokee signed.
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| 1769 | William Bean, supposed to have been first permanent settler in Tennessee builds cabin on Boone's Creek, near its junction with Watauga River.
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| 1772 | The Watauga Association formed; first independent government established in America by native white Americans.
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| 1775 |
Washington District supersedes Watauga Association.
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| 1776 |
July 20. Battle of Island Plats between settlers and Cherokee.
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| 1777 | Washington District becomes Washington County, with boundaries co-extensive with present State of Tennessee. July 20. Commissioners of Virginia and North Carolina negotiate Treaty of Long Island with Cherokee.
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| 1779 |
Jonesboro, first town in Tennessee, established.
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| 1780 |
Rev. Samuel Doak, pioneer evangelist, preaches at Salem.
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| 1781 |
January 15. Battle of Freeland Station between settlers and hostile Cherokee and Creek.
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| 1782 | John Sevier defeats Chickamauga and burns their towns.
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| 1783 |
June 1. McGillivray, Creek chief, forms alliance with Spanish.
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| 1784 |
June 2. North Carolina cedes its western lands to U. S., but repeals act in same year.
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| 1785 |
Davidson Academy, forerunner of University of Nashville and George Peabody College for Teachers, chartered.
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| 1786 |
Treaty of Hopewell between U. S. and Chickasaw. Chickasaw title to West Tennessee recognized by U. S.
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| 1787 |
Franklin Legislature meets at Greeneville for last time.
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| 1788 |
Peter Avery blazes Avery's Trace from East Tennessee across Cumberland Plateau to Nashville.
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| 1789 |
John Sevier elected first Representative to U.S. Congress from Washington.
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| 1790 |
Population, Territorial U. S. Census, 35,691.
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| 1791 |
William Blount, Governor of the Territory South of the River Ohio, establishes headquarters at White's Fort (Knoxville); Knoxville platted.
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| 1792 |
September 10. Andrew Jackson receives his first military appointment, "Judge Advocate for Davidson Regiment."
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| 1793 | September 25. Cavett's Station destroyed by Indians.
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| 1794 |
September 10. Blount College, forerunner of University of Tennessee, chartered (opened 1795).
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| 1795 | The Walton Road completed from Knoxville to Nashville across Cumberland Plateau.
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| 1796 |
February 6. First State constitution adopted.
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| 1797 |
Jackson succeeds William Cocke as U. S. Senator.
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| 1798 | Jackson resigns as U. S. Senator and is appointed judge of State Superior Court.
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| 1800 | Population 105,602. Great religious revival sweeps State.
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| 1802 | Jackson elected major general of militia in contest with John Sevier and James Winchester.
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| 1803 | General Wilkinson builds Fort Pickering at Memphis.
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| 1805 | Aaron Burr visits Nashville on his way to Mississippi territory.
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| 1806 |
May 30. Jackson kills Charles Dickinson in a duel in Logan, Ky.
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| 1807 | Nashville Bank, first in Tennessee, chartered.
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| 1810 |
Population 261,727.
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| 1811 | Bank of the State of Tennessee established.
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| 1812 | September 12. Legislature convenes in Nashville for first time.
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| 1813 |
September 4. Jackson is seriously wounded by Bentons at Talbot (afterward City) Hotel, Nashville.
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| 1814 |
March 27. Jackson defeats Creeks at Battle of Tohopeka, ending Creek War.
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| 1815 |
Manumission Society of Tennessee organized at Lost Creek, Jefferson County.
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| 1818 |
January-May. Jackson ordered to direct campaign against Seminoles; drives Spanish garrison from Pensacola.
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| 1819 |
First steamboat arrives at Nashville.
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| 1820 |
Population 422,823.
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| 1821 | Jackson appointed Territorial Governor of Florida.
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| 1823 |
Pioneer, first newspaper in West Tennessee established at Jackson.
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| 1825 |
Nashoba, Fanny Wright's colony for freed slaves, established.
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| 1826 |
Memphis Advocateestablished - first newspaper in Memphis.
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| 1827 |
Davidson Academy becomes University of Nashville.
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| 1828 |
Jackson defeats John Quincy Adams for presidency of the United States.
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| 1829 |
April. Governor Houston resigns governorship; goes into voluntary exile among Cherokee in Arkansas.
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| 1830 | Population 681,904.
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| 1831 | Railroad Advocate, one of the first newspapers devoted to railroad promotion published at Rogersville.
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| 1833 |
Epidemic of Asiatic cholera sweeps over Tennessee. Large cities paralyzed and many small towns almost depopulated. |
| 1834 | New State constitution adopted.
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| 1835 |
James K. Polk becomes Speaker of the national House of Representatives.
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| 1836 |
Sam Houston and other Tennesseans lead Texans in their war for independence from Mexico.
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| 1837 | Uniform system of public schools in state established by law.
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| 1838 |
Great Removal of Cherokee from Tennessee.
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| 1840 | Population 829,210.
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| 1842 |
First train in Tennessee makes exhibition run over LaGrange and Memphis.
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| 1843 | Nashville becomes State capital.
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| 1844 | November. James K. Polk becomes President-elect.
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| 1845 |
January 1. Work begun on State capitol.
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| 1847 |
New Orleans and Ohio Telegraph Company chartered - first company of kind in Tennessee.
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| 1849 |
Tennessee Historical Society founded.
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| 1850 |
Population, 1,002,717.
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| 1851 |
Col. John Pope wins first prize in cotton exhibit at World's Fair in London.
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| 1853 |
Andrew Johnson, Governor 1853-57.
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| 1854 |
February 28. Gov. Andrew Johnson's recommendation for tax to provide public schools becomes law.
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| 1855 |
State capitol completed.
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| 1860 | Population 1,109,801.
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| 1861 |
May 6. Tennessee, by legislative act, secedes from the Union.
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| 1862 |
February 6. Confederate Fort Henry surrenders.
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| 1863 |
December 31 (1862), January 1, and 2. Battle of Stone's River.
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| 1864 |
September 4. Gen. John H. Morgan killed at Greeneville, East Tennessee.
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| 1865 |
Beginning of Reconstruction.
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| 1866 |
July 19. Tennessee ratifies Fourteenth amendment to U. S. Constitution.
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| 1867 |
Gen. John H. Eaton, Jr., former Union officer, elected State superintendent of public instruction.
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| 1868 | Ku Klux Klan organized at Pulaski.
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| 1869 |
March. Ku Klux Klan disbanded by Gen. Nathan Bedford Forrest, "Grand Cyclops."
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| 1870 |
Population, 1,258,521.
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| 1873 | Educational law passed, establishing uniform system of free public schools.
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| 1875 |
First State board of education created.
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| 1877 | State board of health created.
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| 1878 | Worst yellow fever epidemic in history of U. S. strikes Memphis. Of the 6,000 white population 4,204 died; of the 14,000 Negroes, 946.
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| 1880 |
Population, 1,542,359.
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| 1882 | Julia Doak appointed State superintendent of education, first woman in U. S. to hold such office.
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| 1886 | "The War of the Roses." Robert L. Taylor, Democratic candidate for Governor, defeats his brother, Alfred A. Taylor, Republican candidate.
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| 1890 | Population, 1,767,518.
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| 1891 | July 21. First major strike in Tennessee history called by miners at Coal Creek.
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| 1892 | Steel cantilever bridge over Mississippi at Memphis opened.
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| 1895 | Chickamauga and Chattanooga National Military Park dedicated.
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| 1897 | May 1-November 1. Tennessee Centennial Exposition held at Nashville.
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| 1898 | Tennessee furnishes four regiments for War with Spain.
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| 1899 | County courts given power to establish county high schools and provide for their support and supervision.
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| 1900 | Population 2,020,616.
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| 1907 | Local option law extended to include all cities and towns.
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| 1908 | State militia stops activities of night riders at Reelfoot Lake.
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| 1909 |
The general education bill enacted.
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| 1910 | Population, 2,184,789. Independents elect candidates for the judiciary.
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| 1913 | One-third of the gross revenues of the State appropriated for education. Highway improvement begun. Workmen's compensation law passed.
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| 1917 | April 6. U. S. declares war against Germany. Many Tennesseans volunteer. First Liberty Loan oversubscribed in Tennessee.
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| 1918 |
Sergeant Alvin C. York, with small squad and armed only with pistol and rifle, takes Hill 223 in Argonne Forest.
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| 1919 |
State agrees to furnish $1,000,000, City of Nashville $600,000 and Davidson County $400,000 for memorial building in honor of soldiers of World War.
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| 1920 |
Population, 2,337,885.
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| 1923 | Gov. Austin Peay (1923-1927) puts all activities of State under eight major departments, abolishing about fifty bureaus and departments.
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| 1925 | Scopes evolution trial held at Dayton; William Jennings Bryan and Clarence Darrow are opposing counsel.
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| 1929 |
By agreement with North Carolina, land for Great Smoky Mountains National Park offered to Federal government and accepted.
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| 1930 |
Population, 2,616,556.
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| 1931 |
Legislature investigating committee votes against impeachment of Governor Horton.
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| 1932 | Coal miners strike at Wilder.
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| 1933 |
August 31. Tennessee Valley Authority created by an Act of Congress to develop natural resources of territory within Tennessee River watershed.
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| 1934 | Barnard Astronomical Association founded as a memorial to Dr. Edward Emerson Barnard, Nashville astronomer.
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| 1935 | Rural Electrification Act passed by legislature regulating operation of TVA in State.
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| 1936 |
January. Convict lease law repealed. January. Construction of Chickamauga Dam begun.
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| 1937 |
January. Floods cause much property damage.
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| 1938 | County unit bill invalidated by Tennessee Supreme Court.
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| 1939 | State legislature overrides Governors veto of act to permit, or forbid at county's option, package sales of alcoholic liquor.
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